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Figure 5 Craving and mood scores, and clinical staff opinions The Supplementary Materials report data on participants’ opioid craving scores ( Supplementary Figure S6) changes in positive and negative affect scores ( Supplementary Figure S7 ) and changes in depression, anxiety, and stress scores ( Supplementary Figure S8 ) as well as clinical staff opinions of whether they would favor offering this treatment option ( Supplementary Figure S9 )

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Day 1-2 (Acute Detoxification) Internal systemic detoxification biologically peaks